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A Phase I/II randomized trial of H56:IC31 vaccination and adjunctive cyclooxygenase-2-inhibitor treatment in tuberculosis patients
Host-directed-therapy strategies are warranted to fight tuberculosis. Here we assess the safety and immunogenicity of adjunctive …
Synne Jenum, Kristian Tonby, Corina S. Rueegg, Morten Rühwald, Max P. Kristiansen, Peter Bang, Inge Christoffer Olsen, Kjersti Sellæg, Kjerstin Røstad, Tehmina Mustafa, Kjetil Taskén, Dag Kvale, Rasmus Mortensen, Anne Ma Dyrhol-Riise
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Therapeutic drug monitoring of infliximab compared to standard clinical treatment with infliximab: study protocol for a randomised, controlled, open, parallel-group, phase IV study (the NOR-DRUM study)
BACKGROUND: Infliximab (INX) and other tumour necrosis factor inhibitors (TNFi) have revolutionised the treatment of several immune …
Silje W. Syversen, Guro L. Goll, Kristin K. Jørgensen, Inge C. Olsen, Øystein Sandanger, Johanna E. Gehin, David J. Warren, Joseph Sexton, Cato Mørk, Jørgen Jahnsen, Tore K. Kvien, Nils Bolstad, Espen A. Haavardsholm
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The frequency of intrapartum caesarean section use with the WHO partograph versus Zhang's guideline in the Labour Progression Study (LaPS): a multicentre, cluster-randomised controlled trial
BACKGROUND: There is an ongoing debate concerning which guidelines and monitoring tools are most beneficial for assessing labour …
Stine Bernitz, Rebecka Dalbye, Jun Zhang, Torbjørn M. Eggebø, Kathrine F. Frøslie, Inge Christoffer Olsen, Ellen Blix, Pål Øian
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The Impact of Ultrasound on the Use and Efficacy of Intraarticular Glucocorticoid Injections in Early Rheumatoid Arthritis: Secondary Analyses From a Randomized Trial Examining the Benefit of Ultrasound in a Clinical Tight Control Regimen
OBJECTIVE: Intraarticular glucocorticoid injections are common in rheumatoid arthritis (RA) treatment. This study was undertaken to …
Lena B. Nordberg, Siri Lillegraven, Anna-Birgitte Aga, Joe Sexton, Elisabeth Lie, Hilde B. Hammer, Inge C. Olsen, Till Uhlig, Désirée van der Heijde, Tore K. Kvien, Espen A. Haavardsholm
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Calprotectin as a marker of inflammation in patients with early rheumatoid arthritis
OBJECTIVES: Calprotectin is an inflammatory marker of interest in rheumatoid arthritis (RA). We evaluated whether the level of …
Maria Karolina Jonsson, Nina Paulshus Sundlisæter, Hilde Haugedal Nordal, Hilde Berner Hammer, Anna-Birgitte Aga, Inge Christoffer Olsen, Karl Albert Brokstad, Désirée van der Heijde, Tore K. Kvien, Bjørg Tilde Svanes Fevang, Siri Lillegraven, Espen A. Haavardsholm
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4β-Hydroxycholesterol Level in Patients With Rheumatoid Arthritis Before vs. After Initiation of bDMARDs and Correlation With Inflammatory State
Systemic inflammation has been linked to suppressed CYP3A(4) activity. We determined 4β-hydroxycholesterol (4βOHC), an endogenous …
B. M. Wollmann, S. W. Syversen, E. Lie, C. Gjestad, L. L. Mehus, I. C. Olsen, E. Molden
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A large conditioned pain modulation response is not related to a large blood pressure response: a study in healthy men
BACKGROUND: Endogenous pain modulation has been studied with the conditioned pain modulation (CPM) paradigm with large differences in …
K. B. Nilsen, I. C. Olsen, A. N. Solem, D. Matre
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NORdic trial of oral Methylprednisolone as add-on therapy to Interferon beta-1a for treatment of relapsing-remitting Multiple Sclerosis (NORMIMS study): a randomised, placebo-controlled trial
BACKGROUND: Treatment of relapsing-remitting multiple sclerosis with interferon beta is only partly effective, and new more effective …
Per Soelberg Sorensen, Svein Ivar Mellgren, Anders Svenningsson, Irina Elovaara, Jette Lautrup Frederiksen, Antonie Giaever Beiske, Kjell-Morten Myhr, Lise Vejby Søgaard, Inge Christoffer Olsen, Magnhild Sandberg-Wollheim
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