Severity of Illness Index

Persistent pulmonary pathology after COVID-19 is associated with high viral load, weak antibody response, and high levels of matrix metalloproteinase-9
The association between pulmonary sequelae and markers of disease severity, as well as pro-fibrotic mediators, were studied in 108 …
Tøri Vigeland Lerum, Niklas Nyboe Maltzahn, Pål Aukrust, Marius Trøseid, Katerina Nezvalova-Henriksen, Trine Kåsine, Anne Ma Dyrhol-Riise, Birgitte Stiksrud, Mette Haugli, Bjørn Blomberg, Bård Reiakvam Kittang, Asgeir Johannessen, Raisa Hannula, Saad Aballi, Anders Benjamin Kildal, Ragnhild Eiken, Tuva Børresdatter Dahl, Fridtjof Lund-Johansen, Fredrik Müller, Jezabel Rivero Rodriguez, Carin Meltzer, Gunnar Einvik, Thor Ueland, Inge Christoffer Olsen, NOR-SOLIDARITY Consortium, Andreas Barratt-Due, Trond Mogens Aaløkken, Ole Henning Skjønsberg
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Evaluation of the Effects of Remdesivir and Hydroxychloroquine on Viral Clearance in COVID-19 : A Randomized Trial
BACKGROUND: New treatment modalities are urgently needed for patients with COVID-19. The World Health Organization (WHO) Solidarity …
Andreas Barratt-Due, Inge Christoffer Olsen, Katerina Nezvalova-Henriksen, Trine Kåsine, Fridtjof Lund-Johansen, Hedda Hoel, Aleksander Rygh Holten, Anders Tveita, Alexander Mathiessen, Mette Haugli, Ragnhild Eiken, Anders Benjamin Kildal, Åse Berg, Asgeir Johannessen, Lars Heggelund, Tuva Børresdatter Dahl, Karoline Hansen Skåra, Pawel Mielnik, Lan Ai Kieu Le, Lars Thoresen, Gernot Ernst, Dag Arne Lihaug Hoff, Hilde Skudal, Bård Reiakvam Kittang, Roy Bjørkholt Olsen, Birgitte Tholin, Carl Magnus Ystrøm, Nina Vibeche Skei, Trung Tran, Susanne Dudman, Jan Terje Andersen, Raisa Hannula, Olav Dalgard, Ane-Kristine Finbråten, Kristian Tonby, Bjorn Blomberg, Saad Aballi, Cathrine Fladeby, Anne Steffensen, Fredrik Müller, Anne Ma Dyrhol-Riise, Marius Trøseid, Pål Aukrust, NOR-Solidarity trial
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Active conventional treatment and three different biological treatments in early rheumatoid arthritis: phase IV investigator initiated, randomised, observer blinded clinical trial
OBJECTIVE: To evaluate and compare benefits and harms of three biological treatments with different modes of action versus active …
Merete Lund Hetland, Espen A. Haavardsholm, Anna Rudin, Dan Nordström, Michael Nurmohamed, Bjorn Gudbjornsson, Jon Lampa, Kim Hørslev-Petersen, Till Uhlig, Gerdur Grondal, Mikkel Østergaard, Marte S. Heiberg, Jos Twisk, Kristina Lend, Simon Krabbe, Lise Hejl Hyldstrup, Joakim Lindqvist, Anna-Karin Hultgård Ekwall, Kathrine Lederballe Grøn, Meliha Kapetanovic, Francesca Faustini, Riitta Tuompo, Tove Lorenzen, Giovanni Cagnotto, Eva Baecklund, Oliver Hendricks, Daisy Vedder, Tuulikki Sokka-Isler, Tomas Husmark, Maud-Kristine Aga Ljoså, Eli Brodin, Torkell Ellingsen, Annika Söderbergh, Milad Rizk, Åsa Reckner Olsson, Per Larsson, Line Uhrenholt, Søren Andreas Just, David John Stevens, Trine Bay Laurberg, Gunnstein Bakland, Inge C. Olsen, Ronald van Vollenhoven, NORD-STAR study group
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Predictors of sustained remission in patients with early rheumatoid arthritis treated according to an aggressive treat-to-target protocol
Objectives: To study prognostic factors for achievement of sustained remission in early RA patients receiving semi-personalized tight …
Nina Paulshus Sundlisæter, Inge C. Olsen, Anna-Birgitte Aga, Hilde B. Hammer, Till Uhlig, Désirée van der Heijde, Tore K. Kvien, Siri Lillegraven, Espen A. Haavardsholm, ARCTIC study group
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Clinical and ultrasound remission after 6 months of treat-to-target therapy in early rheumatoid arthritis: associations to future good radiographic and physical outcomes
OBJECTIVE: To explore associations between remission, based on clinical and ultrasound definitions, and future good radiographic and …
Nina Paulshus Sundlisæter, Anna-Birgitte Aga, Inge Christoffer Olsen, Hilde Berner Hammer, Till Uhlig, Désirée van der Heijde, Tore K. Kvien, Siri Lillegraven, Espen A. Haavardsholm, ARCTIC study group
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Calprotectin as a marker of inflammation in patients with early rheumatoid arthritis
OBJECTIVES: Calprotectin is an inflammatory marker of interest in rheumatoid arthritis (RA). We evaluated whether the level of …
Maria Karolina Jonsson, Nina Paulshus Sundlisæter, Hilde Haugedal Nordal, Hilde Berner Hammer, Anna-Birgitte Aga, Inge Christoffer Olsen, Karl Albert Brokstad, Désirée van der Heijde, Tore K. Kvien, Bjørg Tilde Svanes Fevang, Siri Lillegraven, Espen A. Haavardsholm
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Switching from originator infliximab to biosimilar CT-P13 compared with maintained treatment with originator infliximab (NOR-SWITCH): a 52-week, randomised, double-blind, non-inferiority trial
BACKGROUND: TNF inhibitors have improved treatment of Crohn’s disease, ulcerative colitis, spondyloarthritis, rheumatoid …
Kristin K. Jørgensen, Inge C. Olsen, Guro L. Goll, Merete Lorentzen, Nils Bolstad, Espen A. Haavardsholm, Knut E. A. Lundin, Cato Mørk, Jørgen Jahnsen, Tore K. Kvien, NOR-SWITCH study group
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Patients with seronegative RA have more inflammatory activity compared with patients with seropositive RA in an inception cohort of DMARD-naïve patients classified according to the 2010 ACR/EULAR criteria
OBJECTIVES: To compare the presentation of seropositive and seronegative early rheumatoid arthritis (RA) in disease-modifying …
Lena Bugge Nordberg, Siri Lillegraven, Elisabeth Lie, Anna-Birgitte Aga, Inge Christoffer Olsen, Hilde Berner Hammer, Till Uhlig, Maria Karolina Jonsson, Désirée van der Heijde, Tore K. Kvien, Espen Andre Haavardsholm, and the ARCTIC working group
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First step in the development of an ultrasound joint inflammation score for rheumatoid arthritis using a data-driven approach
OBJECTIVES: To develop and validate candidate sets of joints and tendons for assessment of ultrasound (US) joint inflammation in …
Anna-Birgitte Aga, Hilde Berner Hammer, Inge Christoffer Olsen, Till Uhlig, Tore K. Kvien, Désirée van der Heijde, Hallvard Fremstad, Tor Magne Madland, Åse Stavland Lexberg, Hilde Haukeland, Erik Rødevand, Christian Høili, Hilde Stray, Anne Noraas Bendvold, Dag Magnar Soldal, Gunnstein Bakland, Elisabeth Lie, Espen A. Haavardsholm
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Achievement of Remission and Low Disease Activity Definitions in Patients with Rheumatoid Arthritis in Clinical Practice: Results from the NOR-DMARD Study
OBJECTIVE: To examine the frequency of 6 definitions for remission and 4 definitions for low disease activity (LDA) after starting a …
Till Uhlig, Elisabeth Lie, Vibeke Norvang, Åse Stavland Lexberg, Erik Rødevand, Frode Krøll, Synøve Kalstad, Inge C. Olsen, Tore K. Kvien
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